Publications

Also available on ORCID.

* Equal contribution

Peer-reviewed publications

L. Dauban, M. Eder, M. de Haas, V.H. Franceschini-Santos, J.O. Yañez-Cuna, M. Martinovic, T. van Schaik, C. Leemans, H. Teunissen, K. Rademaker, M. Martinez Ara, M. Verkuilen, E. de Wit, B. van Steensel. “Interactions between the genome and the nuclear lamina are multivalent and cooperative”. Nature Structural & Molecular Biology, doi: 10.1038/s41594-025-01655-w (17 July 2025).

In this paper, lamina-associated domains were scrambled using transposon local hopping to create deletions and inversions spanning LADs and flanks. Mapping of subsequent nuclear lamina interactions revealed multivalent and cooperative contacts between LADs and NL. Manuscript reproducibility Transposon integration mapping

M. Olislagers, K. Rademaker, R. A. H. Adan, B. D. Lin & J. J. Luykx. ‘Comprehensive analyses of RNA-seq and genome-wide data point to enrichment of neuronal cell type subsets in neuropsychiatric disorders’. Molecular Psychiatry (27), p947–955, doi: 10.1038/s41380-021-01324-6 (2022).

In this paper, we mapped mouse neuronal cell type gene expression profiles to human orthologs, and conducted robust statistical testing to identify SNPs from 42 neuropsychiatric, substance use and behavioral/quantitative brain-related traits with enrichment in brain cell types. Github repo

Preprints

A. Akbarnejad, L. Steele, D.J. Jafree, S. Birk, M.R. Sallese*, K. Rademaker, A. Boxall, B. Rumney, C. Tudor, M. Patel, M. Prete, S. Makarchuk, T. Li, H. Stanley, A.R. Foster, K. Roberts, A.L. Trinh, C.E. Villa, G. Testa, S. Mahil, A. Mehrjou, C. Smith, S. Vakili, M.R. Clatworthy, T. Mitchell, O.A. Bayraktar, M. Haniffa, M. Lotfollahi. “Mapping and reprogramming microenvironment-induced cell states in human disease using generative AI”. bioRxiv, doi: 10.1101/2025.06.24.661094 (July 24 2025).

L. Dauban, M. Eder, M. de Haas, V.H. Franceschini-Santos, J.O. Yañez-Cuna, T. van Schaik, C. Leemans, K. Rademaker, M. Martinez Ara, M. Martinovic, E. de Wit, B. van Steensel. “Genome - nuclear lamina interactions are multivalent and cooperative”. bioRxiv, doi: 10.1101/2024.01.10.574825 (January 10 2024).

M. Olislagers, K. Rademaker, R. A. H. Adan, B. D. Lin & J. J. Luykx. “Comprehensive analyses of RNA-seq and genome-wide data point to enrichment of neuronal cell type subsets in neuropsychiatric disorders”. bioRxiv, doi: 10.1101/2021.05.06.442982 (July 20 2021).